Last edited by Mahn
Wednesday, May 13, 2020 | History

7 edition of Hepatotoxicity found in the catalog.

Hepatotoxicity

The Adverse Effects of Drugs and Other Chemicals on the Liver

by Hyman J. Zimmerman

  • 91 Want to read
  • 10 Currently reading

Published by Lippincott Williams & Wilkins .
Written in English

    Subjects:
  • Gastroenterology,
  • Hepatology,
  • Medical toxicology,
  • Reference works,
  • Medical / Nursing,
  • Diseases Of The Liver And Biliary Tract,
  • Toxicology,
  • Medical,
  • drug effects,
  • Pharmacology,
  • Medical / Gastroenterology,
  • Drugs,
  • Hepatotoxicology,
  • Liver

  • The Physical Object
    FormatHardcover
    Number of Pages789
    ID Numbers
    Open LibraryOL8094349M
    ISBN 100781719526
    ISBN 109780781719520

    The main purpose of this book is to exhibit relevant, modern information on hepatotoxicity, its symptoms, and treatments presented by internationally recognized experts in the field.   Hepatotoxicity is the medical term for damage to the liver caused by a medicine, chemical, or herbal or dietary supplement. Hepatotoxicity can be a side effect of some HIV medicines. Symptoms of hepatotoxicity can include rash, stomach pain, nausea and vomiting, fatigue, dark-colored urine, light-colored bowel movements, jaundice (yellow skin.

    If you look in a drug book, you will see that many medications may list hepatotoxicity as a potential side effect. In fact, over medications have been associated with causing hepatotoxicity. Between the first and eagerly awaited second edition of Hy’s textbook on hepatotoxicity, 14 more than 20 years elapsed, during which time he collected and memorized more reprints and wrote countless manuscripts and book chapters detailing the clinical, pathological, and laboratory features of nearly all of the newly established hepatotoxic.

    This book addresses all the current, up-to-date developments in this scientific discipline. Liver is the chief metabolizing site in the body, and thus, it is a major target organ for drug and chemical toxicity. Therefore, hepatotoxicity is an important endpoint in the safety evaluation of drugs and chemicals. Drug Hepatotoxicity, An Issue of Clinics in Liver Disease, E-Book. by Nicholaos Pyrsopoulos. The Clinics: Internal Medicine (Book Volume ) Share your thoughts Complete your review. Tell readers what you thought by rating and reviewing this book. Rate it * You Rated it *Brand: Elsevier Health Sciences.


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Hepatotoxicity by Hyman J. Zimmerman Download PDF EPUB FB2

Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the Cited Hepatotoxicity book   This book addresses all the current, up-to-date developments in this scientific discipline.

Liver is the chief metabolizing site in the body, and thus, it is a major target organ for drug and chemical toxicity.

Therefore, hepatotoxicity is an important endpoint in the safety evaluation of. Hepatotoxicity is defined as injury or liver damage caused by exposure to drugs or other nonpharmacological agents [].It is an adverse drug reaction that may be uncommon but serious, and therefore, have a considerable impact on health [].Hepatotoxicity generates between 1/ and 1/ of all hospital admissions, 2–3% of hospitalizations for jaundice, 10% of acute jaundice hepatitis (being Author: Alejandra Cano Paniagua, Pedro Amariles.

Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver.5/5(2).

Hepatotoxicity book. Read reviews from world’s largest community for readers. Written by the foremost authority in the field, this volume is a comprehens Ratings: 0. CTCAE v – Novem Page 4. Blood and lymphatic system disorders CTCAE Term Grade 1 Grade 2 Grade 3 Grade 4 Grade 5.

Anemia Hemoglobin (Hgb) File Size: 2MB. Drug-Induced Liver Disease, 3 rd edition is a comprehensive reference that covers mechanisms of injury, diagnosis and management, major hepatotoxins, regulatory perspectives and much more. Written by highly respected authorities, this new edition is an updated and definitive reference for clinicians and scientists in academia, the.

Drug-Induced Hepatotoxicity: A Review Aashish Pandit, Tarun Sachdeva and Pallavi Bafna ABSTRACT Liver is the principle organ for maintaining the body’s internal environment. There is currently no way to reimburse for the absence of liver function. Its major influence is on the important cause of liver injury.

LIVERTOX is a freely available website that provides up-to-date, comprehensive and unbiased information about drug induced liver injury caused by prescription and nonprescription drugs, herbal products and dietary supplements.

LiverTox represents a collaborative effort by medical and scientific specialists to provide a central repository of clinical information in support of clinical and basic. Management of hepatotoxicity is dependent upon the etymology of the disease, the scale of liver impairment, and the age and overall physical condition of the patient.

Constantly inquire about expert medical guidance about every medication or modification in treatment procedure. Types of liver injury such as fatty liver, necrosis, apoptosis, cholestasis, cirrhosis, hepatitis, oxidative stress and carcinogenesis are described.

Mechanisms of hepatotoxicity are considered along with examples of hepatotoxicants including carbon tetrachloride, ethanol, bromobenzene and acetaminophen. hepatotoxicity: (hep'ă-tō-tok-sis'i-tē), The capacity of a drug, chemical, or other exposure to produce injury to the liver.

Agents with recognized hepatotoxicity include carbon tetrachloride, alcohol, dantrolene sodium, valproic acid, and isonicotinic acid hydrazide. Hepatotoxicity Caused by Specific Anticancer Drugs. Many case reports linking anticancer drugs to hepatotoxicity derive from a period of time when diagnostic tools were more limited.

Sensitive and specific immunoassays were developed for hepatitis A and hepatitis B Cited by: 3. Hepatotoxicity can occur for different reasons and is liver damage that results in your liver not functioning properly. This can be very serious and can further lead to liver failure.

Abstract. This review addresses recent advances in specific mechanisms of hepatotoxicity. Because of its unique metabolism and relationship to the gastrointestinal tract, the liver is an important target of the toxicity of drugs, xenobiotics, and oxidative by: The first edition of this book, published inwas a milestone in defining the important emerging field of drug- and chemical-induced hepatotoxicity.

The second edition offers a thorough, scholarly, and well-written update of more than 2 decades of remarkable by: 2.

Idiosyncratic drug-induced liver injury (DILI) is an underreported and underestimated adverse drug reaction. Information on the documented hepatotoxicity of drugs has recently been made available. This book discusses drug-induced hepatotoxicity in its entirety from details of molecular mechanisms to clinical case presentations.

Special features of drug-induced hepatotoxicity during pregnancy, in pediatric practice, and in the elderly are described. The hepatotoxicity of antifungal medications in bone marrow transplant recipients has been analysed in a retrospective matched-control study (21 C).

The unadjusted incidence of hepatotoxicity was cases per patient-days of exposure to fluconazole (OR = ; 95% CI =). is a rapid access, point-of-care medical reference for primary care and emergency clinicians. Started inthis collection now contains interlinked topic pages divided into a tree of 31 specialty books and chapters.

Hepatotoxicity definition is - a state of toxic damage to the liver. Hepatotoxicity is an injury or liver damage due to exposure to drugs or nonpharmacological agents. It is a rare allergic reaction which can. About GoMedii: GoMedii is a complete healthcare marketplace, where you can Book Appointment With Doctors, Get Online Consultation, Order Medicines Online.Dr.

Pyrsopolous has created a comprehensive review on the most important and timely topics in drug heptatotoxicity. He has arraanged for there to be a full span of very basic articles that discuss drug metabolism, hepatotoxicity, and drug-induced acute liver failure as well as other important articles devoted to clinical manifestations and treatment of drug induced hepatotoxicity; Pathological.